​The Arizona Cardinals and Los Angeles Chargers meet in their 2026 season opener with a matchup that features two dynamic quarterbacks and several explosive playmakers. The Cardinals will lean on QB Kyler Murray and star TE Trey McBride, while the Chargers look to make life difficult behind QB Justin Herbert and one of the AFC’s most talented rosters. One of the key matchups to watch will be whether the Cardinals can slow the Chargers’ passing attack and keep Herbert from making big plays down the field. With both teams looking for a start fast, this game could hinge on which star players make the biggest impact in key moments.Here’s how to watch the game: What time is Chargers vs Cardinals game?Time: 4:25 p.m.What channel is Chargers vs Cardinals game?TV channel: CBSHow to stream Chargers vs Cardinals gameStreaming: FuboWatch Chargers vs Cardinals live on FuboNFL Week 1 game predictions See how various media outlets are picking this week’s NFL games.NFL Week 1 scheduleWednesday, Sept. 9New England Patriots at Seattle Seahawks, 8:20 p.m., NBCThursday, Sept. 10San Francisco 49ers vs. Los Angeles Rams, 8:35 p.m., NetflixSunday, Sept. 13Baltimore Ravens at Indianapolis Colts, 1 p.m., CBSBuffalo Bills at Houston Texans, 1 p.m., CBSCleveland Browns at Jacksonville Jaguars, 1 p.m., CBSNew York Jets at Tennessee Titans, 1 p.m., CBSAtlanta Falcons at Pittsburgh Steelers, 1 p.m., FoxChicago Bears at Carolina Panthers, 1 p.m., FoxTampa Bay Buccaneers at Cincinnati Bengals, 1 p.m., FoxNew Orleans Saints at Detroit Lions, 1 p.m., FoxArizona Cardinals at Los Angeles Chargers, 4:25 p.m., CBSGreen Bay Packers at Minnesota Vikings, 4:25 p.m., CBSMiami Dolphins at Las Vegas Raiders, 4:25 p.m., FoxWashington Commanders at Philadelphia Eagles, 4:25 p.m., FoxDallas Cowboys at New York Giants, 8:20 p.m., NBCMonday, Sept. 14Denver Broncos at Kansas City Chiefs, 8 p.m., ESPN/ABCThis article originally appeared on NorthJersey.com: What channel is Chargers vs Cardinals today? TV, time and predictionOur editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.