​A team that has won and covered 11 of its last 12 games facing an opponent that has yet to cash a ticket this season.The only NFL franchise off to a 4-0 ATS start traveling across the country to play a team that scored the biggest of seven upsets in Week 4.And the latest edition of one of the NFL’s fiercest rivalries — this one featuring a betting line that hasn’t been seen in two decades.Each of these clashes are included in my Week 5 NFL betting trends report — as are two West Coast battles involving four of the top six Super Bowl favorites.Eagles vs. Jaguars (-7.5, 42) in LondonMoneyline: Eagles +280/Jaguars -355• Philadelphia squandered a 20-10 lead at home against the Rams in Week 4, giving up two touchdowns in the final four minutes to lose 24-20 — the team’s second straight defeat.In failing to cash as a 3.5-point home underdog against Los Angeles, the Eagles are now 0-4 ATS to start a season for the first time in franchise history. Philly hasn’t failed to cover in five straight games since ending the 2023 season in an 0-6 ATS funk.• The Jaguars went to Cincinnati in Week 4 and held off the Bengals 22-17 as 2.5-point underdogs.Jacksonville is now riding an 11-1 SU and ATS regular season hot streak. Over this stretch, the Jaguars are 7-0 SU and ATS as a favorite and have tallied eight wins by 14 points or more.• Prior to Sunday’s loss to the Rams, Philadelphia had won five consecutive games as an underdog. The last time the Eagles were a regular-season underdog of more than six points: Week 6 of 2021.On the bright side, Philadelphia has defeated the Jaguars five consecutive times since 2010 (4-1 ATS). In the most recent meeting two years ago, the Eagles prevailed 28-23 but failed to cash as a 7.5-point home favorite.• With this game taking place in London, it’s worth mentioning that Jacksonville is 7-7 SU and ATS at its overseas home since 2013.But here’s the more intriguing NFL betting trend: The winner covered the point spread in all 14 games.• Jacksonville’s defense has now held 11 of its last 12 foes to fewer than 21 points while yielding an average of 14.1 PPG.Conversely, the Eagles are allowing 23.3 PPG across their last six games (playoffs included), surrendering between 20 and 27 points in each one.Orchard Park, NY – October 4: New England Patriots quarterback Drake Maye throws a pass in the first quarter. The New England Patriots played the Buffalo Bills at Highmark Stadium on October 4, 2026. Boston Globe via Getty ImagesRaiders at Patriots (-3.5, 45.5)Moneyline: Raiders +165/Patriots -200• In an AFC West battle of unbeatens, the Raiders came out on the short end of a 30-27 loss to visiting Kansas City in Week 4. Las Vegas did cover the 4.5-point spread, though, to improve to an NFL-best 4-0 ATS. Going back to last season, the Raiders are riding the following positive NFL betting trends: 6-1 ATS overall, 6-1 ATS as an underdog and 3-0 ATS as a visitor.• Patriots quarterback Drake Maye had one touchdown pass a