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The Florida Gators take on the Auburn Tigers in Auburn, AL. Kickoff is set for 7 p.m. ET on ESPN.Florida is favored by -2.5 points on the spread with a moneyline of -130. Auburn, meanwhile, enters as a +2.5 underdog and is +110 on the moneyline to pull off the upset. The over/under sits at 53.5 total points.Here’s my Florida vs. Auburn prediction and college football pick for Saturday, September 19. For more college football picks and analysis, download the Action Network app today.Florida vs. Auburn Pick: Florida ML -130My Auburn vs. Florida best bet is on the Gators to win outright as short road favorites. Find the best line available on our live NCAAF odds page.Florida vs Auburn Odds, Betting Line, Point SpreadFlorida vs Auburn Spread: Florida -2.5, Auburn +2.5Florida vs Auburn Over/Under: 53.5 Total PointsFlorida vs Auburn Moneyline: Florida ML -130, Auburn ML +110The Florida Gators have entered a new era under first-year head coach Jon Sumrall, who had a phenomenal run at Tulane, having led the Green Wave to the 2025 College Football Playoff.Sumrall has been praised for his exceptional offensive mind, and his impact on this Gator program has been evident from the get-go, with Florida scoring a whopping 118 points over the first two games of the 2026 season.Georgia Tech Junior transfer Aaron Philo has been fantastic under center for the Gators, having already thrown for 517 yards and five touchdowns.Florida boasts an explosive group of playmakers on the offensive side of the ball, led by running back Jadan Baugh, who has quickly established himself as one of the premier halfbacks in all of college football. The Gators’ Junior RB ranks amongst the nation’s best in several statistical categories, including 296 rushing yards (4th), five touchdowns (3rd), and 10.6 YPC (4th).Sumrall’s offense balances Baugh’s ground attack with a very talented receiving corps. However, Florida star wide receiver Eric Singleton Jr. has missed the first two games of the season and enters Saturday’s matchup with a questionable designation.The Gators defense has also been under new leadership in 2026, with former Kentucky defensive coordinator Brad White taking over that side of the ball in Gainesville.White specializes in his 3-man and 4-man fronts, largely focusing on stopping the run, generating pressure, and minimizing explosive plays — all aimed at increasing physicality and consistency on the defensive side of the football.Florida’s defense gets its first real test of the season vs. Alex Golesh’s explosive Tigers’ offensive unit led by dual-threat QB Byrum Brown.It’s also a new era for the Auburn Tigers under first-year head coach Alex Golesh was brought in to take over the reins following an abysmal three-year stretch under Hugh Freeze, winning just 15 of 34 games over that stretch.Golesh gained a great reputation as a sharp, offensive-minded coach after a very successful stint as head coach at South Florid