​USA TODAY Sports via Reuters ConnectIt looks like the start of the Los Angeles Rams’ road to the Super Bowl won’t be as easy as they thought in Week 1 after a big injury update on two of the San Francisco 49ers’ best players.There is no doubt the Rams were the biggest winner in the NFL offseason. After pushing the eventual champion Seattle Seahawks to the brink in the NFC Championship Game, they got even better in the spring and summer. Not only did they trade for All-Pro cornerback Trent McDuffie, but they made an even bigger deal by acquiring reigning Defensive Player of the Year and new sack king Myles Garrett.Yet, that wasn’t all. To the surprise of many, Rams legend Aaron Donald decided to come back to the team this summer to see if he was physically capable of returning to the sport after retiring three years ago. Last week, he confirmed, “he’s back,” and added another huge star to a terrifying roster. Unsurprisingly, many are already crowning Los Angeles as the next Super Bowl champs months before the game.George Kittle and Nick Bosa likely to play for San Francisco 49ers in Week 1To start their march to the Big Game at their home stadium in Inglewood early next year, they will take on division rivals the 49ers on the other side of the world in Australia next Thursday. While it won’t be easy, the matchup looks very winnable for the Rams because the availability of San Francisco stars George Kittle and Nick Bosa is unclear. Well, that is no longer the case, according to NFL insider Ian Rapoport.“The 49ers leave today for their game vs the Rams in Australia, and star TE George Kittle will make the trip after 2 positive days of practice, sources say. Kittle is trending in the right direction to play. DE Nick Bosa, ramping up with his knee, will also make the trip.”– Ian RapoportWhat Kittle and Bosa’s returns mean for the Los Angeles Rams in Week 1Outside of a healthy Christian McCaffrey, Kittle ( a seven-time Pro Bowler) and Bosa (a five-time Pro Bowler) are San Francisco’s best players. Having them on the field is a big win for the 49ers to begin the season. It means Brock Purdy will have another great weapon at his disposal on offense, and Rams QB Matthew Stafford needs to worry about where Bosa is lined up at all times.While it is bad news for the Rams, it isn’t too bad. The tight end is coming off a torn Achilles suffered earlier this year, while the star pass rusher is recovering from a knee injury. Both are serious issues, and the 49ers are sure to be very cautious with both this early in the season. Although both will likely play on Thursday, they are going to have a limited number of snaps. Meaning that this is still a very winnable division matchup for Los Angeles.Related HeadlinesMinnesota Vikings Sign 2x Super Bowl Champion DefenderHouston Texans Set to Bench 3x Pro Bowl Player in Week 1Predicting NFL QBs Benched in 2026: Projecting Current Starters Who Will Get Demoted and When It HappensRead more at Sp