​Clemson football is entering a critical season after going 7-6 in 2025, the worst under coach Dabo Swinney since 2010. The Tigers will have a new starting quarterback. Senior Christopher Vizzina has been the backup for two years and is expected to take the job. He is competing with freshman Tait Reynolds.Clemson has plenty of other questions, especially with Chad Morris back as offensive coordinator for the second time. The Tigers will turn to Gideon Davidson as the lead running back. They’ll have a reshuffled offensive line after losing four starters.Clemson is ranked No. 23 in the US LMB Coaches Poll to start the season.Here are game-by-game predictions for Clemson in 2026. Clemson score predictions for 2026 college football season Sept. 5: Clemson at LSU Location, time: Tiger Stadium; Baton Rouge, Louisiana | 7:30 p.m. ET (ABC) About the game: Coaches will be in the biggest spotlight in this game. For LSU, it will be the debut of Lane Kiffin after his departure from Ole Miss following the 2025 regular season. For Clemson, it’s an early chance for Swinney to answer critics who believe he will be on the hot seat this season. Score prediction: LSU 38, Clemson 28Sept. 12: Georgia Southern at Clemson Location, time: Memorial Stadium, Clemson | 7:30 p.m. About the game: Clemson should be able to take care of Georgia Southern in the home opener and get that first win. It should be noted, however, that Georgia Southern beat Nebraska, 45-42, in 2022 and Cornhuskers coach Scott Frost was fired the next day. The Eagles won’t be a pushover.Score prediction: Clemson 35, Georgia Southern 24 Sept. 19: North Carolina at Clemson  Location, time: Memorial Stadium | Noon (ESPN) About the game: Six-time Super Bowl winning coach Bill Belicheck will be on the sideline at Clemson for the first time since taking over the program at North Carolina in 2025. But this is not the New England Patriots. The Tar Heels were picked No. 15 of 17 teams in the ACC. Score prediction: Clemson 38, North Carolina 10Sept. 25: Clemson at Cal Location, time: California Memorial Stadium; Berkeley, California | 10:30 p.m. ET About the game: This is just going to feel weird. It’s a Friday night kickoff after most high school games have wrapped up. It’s an ACC game in California. It’s at a stadium with Alcatraz in the background. Clemson survives the weirdness and goes 2-0 in the ACC. Score prediction: Clemson 27, Cal 17Oct. 3: Miami at Clemson  Location: Memorial StadiumAbout the game: This could be the most important game of the season for Clemson. Miami was picked as the overwhelming favorite in the ACC, and quarterback Darian Mensah was voted preseason player of the year. No kickoff time set. Feels like a prime-time game and could be a prime opportunity for an upset. Score prediction: Miami 20, Clemson 17 Oct. 17: Charleston Southern at Clemson Location: Memorial StadiumAbout the game: Clemson will be coming off an open date following the Mia