​The Eagles have lost another key player to injury against the Rams, as cornerback Quinyon Mitchell is questionable to return with a knee injury, the team announced. Jonathan Jones entered at cornerback for Mitchell. The change adds responsibility to Philadelphia’s secondary as it adjusts to losing a starting corner during the game.Mitchell’s status matters against a Rams passing attack led by Matthew Stafford and featuring Puka Nacua. Philadelphia already entered the matchup without safety Marcus Epps, who was inactive with a groin injury. The Eagles also were missing linebacker Zack Baun and wide receiver DeVonta Smith, among others.Jones was available after being listed with a quadriceps injury earlier in the week and practicing fully on Friday. He now has an opportunity to take on a larger role while Mitchell is evaluated.Injury Update: CB Quinyon Mitchell (knee) is questionable to return.— Philadelphia Eagles (@Eagles) October 4, 2026The Eagles had not provided details on how Mitchell was injured or whether he would return. His designation is questionable, leaving open the possibility that he could re-enter if cleared.Philadelphia will need its remaining defensive backs to maintain coverage and communication while Mitchell is sidelined. Any extended absence would further test the secondary’s depth against Los Angeles.This article originally appeared on Eagles Wire: Quinyon Mitchell exits Eagles matchup vs. Rams with a knee injury