​The toughest lineup decisions in fantasy football are the last ones. With your top draft picks and emerging stars, it’s easy to lock those players in as every-week starters. But in leagues that have roster spots available for a flex position (RB, WR or TE), the choices can be agonizing. There are injury concerns, matchups and statistical trends to take into consideration. So with a fresh slate of NFL games set to kick off, we’ve put together some overall Flex rankings to help you with your most difficult lineup calls. Below are our combined top 150 running backs, wide receivers and tight ends, ranked by their projected fantasy points in Week 3.WEEK 3 FANTASY RANKINGS:QB | RB | WR | TE | K | D/STTiered fantasy football Flex rankings for Week 3Using USA TODAY Sports Fantasy’s stat projections, here are the Flex rankings for Week 3 using a half-point PPR scoring system. Tier 1 (Lineup locks)These players are must-starts at your starting running back and wide receiver spots in all leagues. If you need to flex a player in this tier, congratularions on your super team.1 RB Jahmyr Gibbs DET2 RB Kenneth Walker III KC3 RB Bijan Robinson ATL4 RB Christian McCaffrey SF5 RB Derrick Henry BAL6 RB Ashton Jeanty LV7 RB James Cook III BUF8 WR Jaxon Smith-Njigba SEA9 RB Jonathan Taylor IND10 WR Ja’Marr Chase CIN11 WR Amon-Ra St. Brown DET12 RB Chase Brown CIN13 WR Justin Jefferson MIN14 RB Breece Hall NYJ15 RB Omarion Hampton LAC16 RB Saquon Barkley PHI17 RB De’Von Achane MIA18 WR Chris Olave NO19 RB Javonte Williams DAL20 TE Trey McBride ARI21 RB Kyren Williams LAR22 RB Chuba Hubbard CAR23 WR CeeDee Lamb DAL24 WR DeVonta Smith PHI25 RB D’Andre Swift CHI26 RB David Montgomery HOU27 RB Bucky Irving TBTier 2 (Confidence picks)28 WR Drake London ATL29 RB Cam Skattebo NYG30 WR Garrett Wilson NYJ31 WR Zay Flowers BAL32 RB Aaron Jones Sr. MIN33 RB Jaylen Warren PIT34 RB Quinshon Judkins CLE35 WR Parker Washington JAC36 WR George Pickens DAL37 WR Christian Watson GB38 WR Mike Evans SF39 WR Puka Nacua LAR40 WR Malik Nabers NYG41 RB Bhayshul Tuten JAC42 WR Davante Adams LAR43 WR Rashee Rice KC44 WR Tee Higgins CIN45 RB Jeremiyah Love ARI46 WR Jaylen Waddle DEN47 RB Travis Etienne Jr. NO48 RB TreVeyon Henderson NE49 WR Ladd McConkey LAC50 WR Tetairoa McMillan CARTier 3 (Solid contributors)51 WR Matthew Golden GB52 TE Brock Bowers LV53 TE Dalton Kincaid BUF54 WR Jameson Williams DET55 TE Sam LaPorta DET56 WR Emeka Egbuka TB57 WR Jalen Coker CAR58 WR Deebo Samuel Sr. SF59 TE Tucker Kraft GB60 TE George Kittle SF61 TE Travis Kelce KC62 WR DK Metcalf PIT63 RB Jadarian Price SEA64 WR Adonai Mitchell NYJ65 TE Tyler Warren IND66 WR Terry McLaurin WAS67 TE Dalton Schultz HOU68 WR Romeo Doubs NE69 WR Denzel Boston CLE70 TE Isaiah Likely NYG71 RB Rhamondre Stevenson NE72 WR Stefon Diggs WAS73 WR Josh Downs IND74 WR Devaughn Vele NO75 TE Colston Loveland CHI76 WR Xavier Worthy KC77 RB Tony Pollard TEN78 WR DJ Moore BUF79 WR Dontayvion Wicks PHITier 4 (Matchup plays)80 RB Jacory Crosk