​Duke football looks to start its season 4-0 for the second time under head coach Manny Diaz as they host William & Mary on Saturday, Sept. 26, at Wallace Wade Stadium.The Blue Devils are coming off an impressive 35-7 win over Stanford as they opened ACC play, while William & Mary (2-2) is coming off a 52-27 loss to Fordham. In their first matchup since 1955, Duke has an opportunity to gain some ground on the all-time series record, which William & Mary currently leads 6-1.Here’s how to watch Duke football vs. William & Mary on TV and streaming, along with betting odds, picks and predictions.Stream Duke vs. William & MaryWhat channel is Duke vs. William & Mary on today?TV Channel: ACC Network ExtraLivestream: Fubo (free trial)Duke vs. William & Mary will air on ACC Network Extra in Week 4 of the 2026 college football season. Kevin Fitzgerald (play-by-play) and Jeff Woody (analyst) will call the game from the booth at Wallace Wade Stadium. You can stream the game on FUBO, which offers a free trial to new subscribers.Duke vs. William & Mary time tomorrowDate: Saturday, Sept. 26Start time: 3:30 p.m.Kickoff between Duke and William & Mary begins at 3:30 p.m. ET on Saturday, Sept. 26 at Wallace Wade Stadium in Durham, North Carolina.Stream Duke vs. William & MaryDuke vs. William & Mary predictions, picks, oddsOdds courtesy of BetMGM as of Friday, Sept. 25Duke 45, William & Mary 3: The Blue Devils will ride the Nate Sheppard wave to yet another win in Week 4. Sheppard has been unstoppable, rushing for an FBS-leading 528 rushing yards and eight total touchdowns, tied for the most by a non-QB. Then there’s Duke’s defense, which has refound its form from Manny Diaz’s first season in Durham. All the while, Walker Eget is becoming increasingly comfortable managing the game. – Zach CiavolellaSpread: Duke -43.5Over/under: 62.5Moneyline: Unlisted (heavy favorite)Contact/Follow us @DukeWire on X (formerly Twitter) and like our page on Facebook to follow ongoing coverage of Duke news, notes, and opinions. Follow Zach on X: @CiavoNBAThis article originally appeared on Duke Wire: What channel is Duke vs William & Mary on? Time, TV for Week 4Our editors independently choose our recommendations. Some content is produced with paid support from a third party, however our editorial decisions remain independent. If you buy through our links, the USA TODAY Network may earn a commission. Prices and availability may change.